TIMM44 is the essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. It recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
Pathway
Metabolism of proteins, organism-specific biosystem; Mitochondrial Protein Import, organism-specific biosystem;
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