Anti-TIMM17B monoclonal antibody (DCABH-201588) Made to order

Rabbit anti-Human TIMM17B monoclonal antibody for WB, ELISA Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human TIMM17B is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
TIMM17B; translocase of inner mitochondrial membrane 17 homolog B (yeast); JM3; TIM17B; DXS9822; mitochondrial import inner membrane translocase subunit Tim17-B
Entrez Gene ID
UniProt ID

Product Background


Gene summary
TIMM17B (Translocase Of Inner Mitochondrial Membrane 17 Homolog B (Yeast)) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Mitochondrial protein import. GO annotations related to this gene include P-P-bond-hydrolysis-driven protein transmembrane transporter activity. An important paralog of this gene is TIMM17A. This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants.
Antigen Description
This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. The function about TIMM17B antigen include P-P-bond-hydrolysis-driven protein transmembrane transporter activity.
Pathway
Metabolism of proteins; Mitochondrial Protein Import.

Citations


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References


Monaco, E; Bionaz, M; et al. Selection and reliability of internal reference genes for quantitative PCR verification of transcriptomics during the differentiation process of porcine adult mesenchymal stem cells. STEM CELL RESEARCH & THERAPY 1:-(2010).

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