Anti-TIMM10 (aa 1-90) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

antigen sequence: MDPLRAQQLA AELEVEMMAD MYNRMTSACH RKCVPPHYKE AELSKGESVC LDRCVSKYLD IHERMGKKLT ELSMQDEELM KRVQQSSGPA, corresponding to N terminal amino acids 1-90 of Human TIMM10.

Conjugate

Application Notes

IHC-P: 1/50 - 1/200. WB: 1/250 - 1/500. ICC/IF: 1 - 4 μg/ml.

Alternative Names

TIMM10; translocase of inner mitochondrial membrane 10 homolog (yeast); TIM10; TIM10A; mitochondrial import inner membrane translocase subunit Tim10;

Entrez Gene ID

UniProt ID

Antigen Description

Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

Pathway

Metabolism of proteins;