Recombinant full length protein corresponding to Human Tcl1 aa 1-114.Sequence: MAECPTLGEAVTDHPDRLWAWEKFVYLDEKQHAWLPLTIEIKDRLQLRVL LRREDVVLGR PMTPTQIGPSLLPIMWQLYPDGRYRSSDSSFWRLVYHI KIDGVEDMLLELLPDD Database link: P56279
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/50 - 1/200; WB: 1/500 - 1/2000;
Target
Alternative Names
TCL1A; T-cell leukemia/lymphoma 1A; TCL1; T-cell leukemia/lymphoma protein 1A; oncogene TCL1; oncogene TCL-1; protein p14 TCL1; T-cell lymphoma-1;
Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
Pathway
PI3K-Akt signaling pathway;
Citations
Publication ()
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