TCEB3 (NP_003189, 81 a.a. ~ 190 a.a) partial recombinant protein with GST tag. The sequence is NAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELE RPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMY
Conjugate
Unconjugated
Target
Alternative Names
TCEB3; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); EloA; SIII; TCEB3A; SIII p110; transcription elongation factor B polypeptide 3; elongin-A; elongin 110 kDa subunit; transcription elongation factor B alpha subunit; RNA po
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Pathway
Disease; Formation of HIV-1 elongation complex containing HIV-1 Tat; Gene Expression; HIV Life Cycle.
Citations
Publication ()
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