Anti-TBX3 (aa 311-410) polyclonal antibody

Species Reactivity

Human

Immunogen

TBX3 (NP_005987, 311 a.a. ~ 410 a.a) partial recombinant protein with GST tag. The sequence is KENGTSDESSSEQAAFNCFAQASSPAASTVGTSNLKDLCPSEGESDAEAESKEEHGPEAC DAAKISTTTSEEPCRDKGSPAVKAHLFAAERPRDSGRLDK

Conjugate

Alternative Names

TBX3; T-box 3; UMS; XHL; TBX3-ISO; T-box transcription factor TBX3; T-box protein 3; bladder cancer related protein XHL;

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.