Anti-TBK1 monoclonal antibody (DCABH-462)

Mouse anti-Human TBK1 monoclonal antibody for WB, IHC-P Datasheet

Online Inquiry Add to basket   

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
219B530
Species Reactivity
Human
Immunogen
Synthetic peptide: YYQFKKDKAERRLAYC conjugated to KLH, corresponding to amino acids 563-577 of Human NAK (NP_037386.1).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 - 2 μg/ml; IHC-P: 10 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TBK1; TANK-binding kinase 1; serine/threonine-protein kinase TBK1; NAK; NF-kB-activating kinase; NF-kappa-B-activating kinase
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; Hepatitis C, organism-specific biosystem;

Citations


Have you cited DCABH-462 in a publication? Let us know and earn a reward for your research.

References


Parker, D; Martin, FJ; et al. Streptococcus pneumoniae DNA Initiates Type I Interferon Signaling in the Respiratory Tract. MBIO 2:-(2011).
Vilasco, M; Larrea, E; et al. The protein kinase IKK epsilon can inhibit HCV expression independently of IFN and its own expression is downregulated in HCV-infected livers. HEPATOLOGY 44:1635-1647(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-TBK1 monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket