This product (Catalog No. DPABH-19506) is a rabbit-derived polyclonal antibody raised against human TBCK. This antibody exhibits cross-reactivity with TBCK from mouse. It has been affinity purified by Protein A. This gene encodes a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. The encoded protein is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR complex. Alternative splicing results in multiple transcript variants. DPABH-19506 is suitable for use in IHC (1:30–1:150) application. DPABH-19506 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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