Anti-TAF1D polyclonal antibody (DPABH-11397)

Rabbit anti-Human TAF1D (aa 69-98) polyclonal antibody for FC, IHC-P, WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Human
Immunogen
Synthetic peptide within Human TAFD1 aa 69-98 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q9H5J8
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 1/10 - 1/50; IHC-P: 1/50 - 1/100; WB: 1/100 - 1/500;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TAF1D; TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa; JOSD3; RAFI41; TAFI41; TAF(I)41
Entrez Gene ID
UniProt ID

Product Background


Gene summary
TAF1D (TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit D) is a Protein Coding gene. Among its related pathways are Gene Expression and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al. , 2004 [PubMed 15520167]; Gorski et al. , 2007 [PubMed 17318177]).
Antigen Description
TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al. , 2004 [PubMed 15520167]; Gorski et al. , 2007 [PubMed 17318177]). Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. The function about TAF1D antigen include DNA binding; protein binding.
Pathway
Epigenetic regulation of gene expression; Negative epigenetic regulation of rRNA expression; RNA Polymerase I Chain Elongation; RNA Polymerase I Promoter Escape.

Citations


Have you cited DPABH-11397 in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Pijnappel, WWMP; Kolkman, A; et al. Quantitative mass spectrometry of TATA binding protein-containing complexes and subunit phosphorylations during the cell cycle. PROTEOME SCIENCE 7:-(2009).

Online Inquiry

Name:
Phone: *
E-mail Address: *
Service & Products Interested: *
Project Description:
Verification Code: * Please input "diagnostics" as verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket