Specifications
Species Reactivity
Mouse; Human
Immunogen
Synthetic peptide within Human TAFD1 aa 69-98 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q9H5J8
Applications
Application Notes
Flow Cyt: 1/10 - 1/50; IHC-P: 1/50 - 1/100; WB: 1/100 - 1/500;
Target
Alternative Names
TAF1D; TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa; JOSD3; RAFI41; TAFI41; TAF(I)41; TATA box-binding protein-associated factor RNA polymerase I subunit D; TBP-associated factor 1D; Josephin domain containing 3; TATA box-b
Product Background
Antigen Description
TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 17318177]).
Pathway
Epigenetic regulation of gene expression; Negative epigenetic regulation of rRNA expression; RNA Polymerase I Chain Elongation; RNA Polymerase I Promoter Escape.
Citations
Publication ()
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COA
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