General Notes
This product (Catalog No. DPABH-15929) is a rabbit-derived polyclonal antibody raised against human TADA3, targeting the amino acid region 149–340 of the protein. It has been affinity purified by Protein A. TADA3L, also known as TADA3 (transcriptional adaptor 3), is a human protein-coding gene located on chromosome 3p25.3 that encodes a transcriptional coactivator protein critical for regulating gene expression through histone acetylation and chromatin remodeling. The TADA3 protein serves as a subunit of multiple histone acetyltransferase (HAT) complexes, including the ADA2A-containing ATAC complex and the SPT3-TAF9-GCN5/PCAF STAGA complex, where it facilitates the acetylation of histones in nucleosomal contexts to promote transcriptional activation by linking DNA-binding activators to the basal transcriptional machinery. It is ubiquitously expressed across human tissues, with particularly high levels in testis and ovary, and alternative splicing produces multiple isoforms, including protein-coding variants a and b.
DPABH-15929 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-15929 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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