This gene encodes a seven-transmembrane G-protein-coupled receptor that likely functions as a receptor for endogenous trace amines. Mutations in this gene may be associated with schizophrenia.
Pathway
Amine ligand-binding receptors; Class A/1 (Rhodopsin-like receptors); G alpha (s) signalling events; GPCR downstream signaling; GPCR ligand binding; Neuroactive ligand-receptor interaction; Signal Transduction; Signaling by GPCR.
Citations
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