Orphan receptor. Ligands are likely small molecules, either sharing some similarities with trace amine as, e.g. derivatives of indolamines (such as 5-methoxytryptamine) or of phenylethylamines (such as phenylethanolamine) or being any kind of metabolite of amino acids or biogenic amine neurotransmitters.
Pathway
Amine ligand-binding receptors; G alpha (s) signalling events; GPCR ligand binding; Neuroactive ligand-receptor interaction
Citations
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