The protein encoded by this gene is an embryonic nucleartranscription factor that binds to a specific DNA element, thepalindromic T-site. It binds through a region in its N-terminus,called the T-box, and effects transcription of genes required formesoderm formation and differentiation. The protein is localized tonotochord-derived cells.
Pathway
Cardiac Progenitor Differentiation; Regulation of Wnt-mediated beta catenin signaling and target gene transcription
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