Specifications
Immunogen
Recombinant Human Sumo 2 (1-93aa; MADEKPKEGV KTENNDHINL KVAGQDGSVV QFKIKRHTPL SKLMKAYCER QGLSMRQIRF RFDGQPINET DTPAQLEMED EDTIDVFQQQ TGG) purified from E. coli.
Applications
Application Notes
WB: 1/250 - 1/500; ELISA: 1/250; ICC/IF: 1/250 - 1/500;
Target
Alternative Names
SUMO3; SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae); SMT3 (suppressor of mif two 3, yeast) homolog 1 , SMT3 suppressor of mif two 3 homolog 3 (yeast) , SMT3H1; small ubiquitin-related modifier 3; SMT3A; SUMO-2; SMT3 homolog 1; ubiquitin-like pr
Product Background
Antigen Description
SUMO proteins, such as Sumo 2 and Sumo 3, post-translationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. Sumo 2 and Sumo 3 are highly homologous, hence it is very difficult to produce antibodies which distinguish them.
Pathway
Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Nuclear pore complex, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem;
Citations
Publication ()
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