This product (Catalog No. DPABH-04127) is a rabbit-derived polyclonal antibody raised against human SERTAD1. It has been affinity purified by Protein A. SERTAD1 (SERTA domain-containing protein 1), also known as TRIP-Br1 or p34SEI-1, is a multi-functional protein primarily known as a transcriptional co-regulator and a critical regulator of the cyclin D/CDK4 cell cycle machinery. It promotes G1/S cell cycle progression by inhibiting p16INK4a and has significant roles in tumorigenesis, apoptosis, and cellular stress responses. Recent studies show it acts as an adaptor in the cytoplasm, regulating NLRP3 inflammasome activation. DPABH-04127 is suitable for use in IHC (1:20–1:100) application. DPABH-04127 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
SEI1; TRIP-Br1; SERTAD1; SERTA domain-containing protein 1; p34SEI-1
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