General Notes
This product (Catalog No. DPABH-23981) is a rabbit-derived polyclonal antibody raised against human SYT7, targeting the amino acid region 137–403 of the protein. It has been affinity purified by Protein A. Synaptotagmin-7 (SYT7), also known as synaptotagmin VII, is a protein encoded by the SYT7 gene located on the long arm of human chromosome 11 at position 11q12.2. As a member of the synaptotagmin family of vesicle-associated proteins, SYT7 features a transmembrane domain and two C2 domains that bind calcium ions (Ca²⁺) with high affinity but slow kinetics, enabling it to sense lingering submicromolar Ca²⁺ elevations. The protein, consisting of 403 amino acids in its major isoform, is widely expressed in brain tissues, prostate, and other organs, with multiple splice variants influencing its localization to presynaptic membranes, lysosomes, and the plasma membrane.
DPABH-23981 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-23981 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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