Synaptotagmin 4 (SYT4) belongs to the synaptotagmin family of multi-domained, integral membrane proteins of synaptic vesicles. It may be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. It is primarily expressed in the brain.
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