Specifications
Immunogen
SYNJ1 (NP_003886, 1474 a.a. ~ 1573 a.a) partial recombinant protein with GST tag. The sequence is KISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVL PSRRPPPPPVPLLPPGTSPPVDPFTTLASKASPTLDFTER
Target
Alternative Names
SYNJ1; synaptojanin 1; INPP5G; PARK20; synaptojanin-1; inositol 5-phosphatase (synaptojanin 1); synaptojanin-1, polyphosphoinositide phosphatase; synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1;
Product Background
Antigen Description
This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene.
Pathway
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian); D-myo-inositol (1,3,4)-trisphosphate biosynthesis; EPHB forward signaling; Internalization of ErbB1
Citations
Publication ()
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COA
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