Anti-SUMO4 (aa 49-63) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to Human SUMO4 aa 49-63 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).Sequence: CEPRGLSMKQIRFRFG Database link: Q6EEV6 Run BLAST with Run BLAST with

Conjugate

Application Notes

IHC-P: 1/50 - 1/100; WB: 1/100 - 1/500.

Alternative Names

SUMO4; SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae); SMT3 suppressor of mif two 3 homolog 4 (yeast); SMT3H4; small ubiquitin-related modifier 4; dJ281H8.4; SMT3 suppressor of mif two 3 homolog 2; small ubiquitin-like modifier 4 protein; IDDM5; S

Entrez Gene ID

UniProt ID

Antigen Description

Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.

Pathway

Nuclear pore complex; RNA transport;