Anti-SUCLA2 (aa 200-300) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Human

Immunogen

Synthetic peptide corresponding to Human SUCLA2 aa 200-300 conjugated to Keyhole Limpet Haemocyanin (KLH).Database link: Q9P2R7

Conjugate

Application Notes

IHC-P: 5μg/ml; WB: 1/250;

Alternative Names

SUCLA2; succinate-CoA ligase, ADP-forming, beta subunit; A-BETA; MTDPS5; SCS-betaA; succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; renal carcinoma antigen NY-REN-39; succinyl-CoA synthetase beta-A chain; ATP-specific succinyl-CoA synthetas

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Pathway

Carbon metabolism; Citrate cycle (TCA cycle); Citrate cycle (TCA cycle, Krebs cycle); Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate