Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Munc18c aa 550 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: O00186
Applications
Application Notes
WB: 1/10000 - 1/50000; ICC/IF: 1/100 - 1/250; IP: 1/10 - 1/100;
Target
Alternative Names
STXBP3; syntaxin binding protein 3; syntaxin-binding protein 3; UNC 18C; unc18-3; platelet Sec1 protein; protein unc-18 homolog 3; protein unc-18 homolog C; syntaxin 4 binding protein; PSP; MUNC18C; UNC-18C; MUNC18-3;
Product Background
Antigen Description
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Pathway
Disinhibition of SNARE formation, organism-specific biosystem; Hemostasis, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem;
Citations
Publication ()
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COA
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