Anti-STX5 (aa 1-100) polyclonal antibody

Species Reactivity

Human

Immunogen

STX5A (NP_003155, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MSCRDRTQEFLSACKSLQTRQNGIQTNKPALRAVRQRSEFTLMAKRIGKDLSNTFAKLEK LTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQ

Conjugate

Alternative Names

STX5; syntaxin 5; SED5; STX5A; syntaxin-5; syntaxin 5A;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Pathway

SNARE interactions in vesicular transport;