Anti-STRBP polyclonal antibody (DPABH-01776)

Rabbit anti-Human STRBP (aa 1-165) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-165 of Human STRBP.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/3,000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
STRBP; spermatid perinuclear RNA binding protein; p74; SPNR; ILF3L; HEL162
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3-UTR and adenovirus VA RNA. Spermatid perinuclear RNA-binding protein is a protein that in humans is encoded by the STRBP gene. 0The function about STRBP antigen include DNA binding; double-stranded RNA binding; poly(A) RNA binding; single-stranded RNA binding.

Citations


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References


Wu, ATH; Sutovsky, P; et al. The postacrosomal assembly of sperm head protein, PAWP, is independent of acrosome formation and dependent on microtubular manchette transport. DEVELOPMENTAL BIOLOGY 312:471-483(2007).
OKO, R; MORALES, CR; et al. A NOVEL TESTICULAR PROTEIN, WITH SEQUENCE SIMILARITIES TO A FAMILY OF LIPID-BINDING PROTEINS, IS A MAJOR COMPONENT OF THE RAT SPERM PERINUCLEAR THECA. DEVELOPMENTAL BIOLOGY 166:235-245(1994).

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