Specifications
Immunogen
A synthetic peptide of human ST8SIA4 is used for rabbit immunization.
Target
Alternative Names
ST8SIA4; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; sialyltransferase 8 (alpha 2, 8 polysialytransferase) D , SIAT8D; CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; PST; PST1; ST8Sia IV; SIAT8-D; ST8SiaIV; sialyltransferase 8
Product Background
Antigen Description
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
Pathway
Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; NCAM1 interactions, organism-specific biosystem.
Citations
Publication ()
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COA
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