Specifications
Immunogen
Recombinant fragment, corresponding to a region within amino acids 83-255 of Human ST6GALNAC4 (Q9H4F1).
Applications
Application Notes
WB: 1/500 - 1/3000.
Target
Alternative Names
ST6GALNAC4; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; sialyltransferase 7D ((alpha N acetylneuraminyl 2,3 beta galactosyl 1,3) N acetyl galactosaminide alpha 2,6 sialyltransferase); SIAT
Product Background
Antigen Description
Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. Prefers glycoproteins to glycolipids.
Pathway
Glycosphingolipid biosynthesis - ganglio series; Metabolic pathways; Metabolism of proteins; O-linked glycosylation of mucins; Post-translational protein modification; Termination of O-glycan biosynthesis;
Citations
Publication ()
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COA
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