Specifications
Immunogen
A synthetic peptide of human ST3GAL1 is used for rabbit immunization.
Target
Alternative Names
ST3GAL1; ST3 beta-galactoside alpha-2,3-sialyltransferase 1; sialyltransferase 4A (beta galactosidase alpha 2,3 sialytransferase) , SIAT4A; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; SIATFL; ST3Gal I; ST3GalA.1; ST3O; SIAT4-
Product Background
Antigen Description
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet.
Pathway
Glycosaminoglycan biosynthesis - keratan sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - keratan sulfate, conserved biosystem; Glycosphingolipid biosynthesis - ganglio series, organism-specific biosystem; Glycosphingolipid biosynthesis - ganglio series, conserved biosystem; Glycosphingolipid biosynthesis - globo series, organism-specific biosystem; Glycosphingolipid biosynthesis - globo series, conserved biosystem; Metabolic pathways, organism-specific biosystem.
Citations
Publication ()
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COA
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