Rabbit Anti-Human SSTR2 (a.a. 1-60) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human SSTR2 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-60 aa of BC019610

Conjugate

Application Notes

IHC: 1:200-1:800
IF/ICC: 1:200-1:800

General Notes

This product (Catalog No. DPABH-02572) is a rabbit-derived polyclonal antibody raised against human SSTR2, targeting the amino acid region 1–60 of the protein. This antibody exhibits cross-reactivity with Human SSTR2 from mouse. It has been affinity purified by Protein A. Somatostatin receptor 2 (SSTR2) is a G-protein coupled membrane receptor expressed in a variety of neural and neurosecretory tissue types. In neuroendocrine tumors (NETs), in which Somatostatin receptors (SSTRs) are commonly expressed, the detection of SSTR2 expression has both diagnostic and therapeutic potential. Besides NETs, SSTR2 immunostaining can be detected in other types of tumor cells(PMID:34786053). Moreover, SSTR2 is consistently expressed in Olfactory neuroblastoma (ONB) suggesting a role for somatostatin-analog based imaging and therapy in this disease. More generally, SSTR2 may be another marker of neuroendocrine diferentiation in ONB(PMID:33929681). SSTR2 has 2 isoforms with the MW of 40-41 kDa.
DPABH-02572 is suitable for use in IHC (1:200–1:800), IF/ICC (1:200–1:800) applications.
DPABH-02572 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

somatostatin receptor 2; Somatostatin receptor type 2; SRIF 1; SRIF-1; SS 2 R

Entrez Gene ID

UniProt ID