Specifications
Immunogen
Synthetic peptide corresponding to residues in Human Somatostatin Receptor 1.
Applications
Application Notes
WB: 1/500; ICC/IF: 1/250 - 1/500;
Target
Alternative Names
SSTR1; somatostatin receptor 1; somatostatin receptor type 1; G-protein coupled receptor; SS1R; SS1-R; SRIF-2; SS-1-R;
Product Background
Antigen Description
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Citations
Publication ()
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COA
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