The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times.
Pathway
Gene Expression; Metabolism of proteins; Protein processing in endoplasmic reticulum; SRP-dependent cotranslational protein targeting to membrane; Translocon-associated protein (TRAP) complex;
Citations
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