Anti-SSEA-3 monoclonal antibody (DMAB12907)
Rat anti-Mouse SSEA-3 monoclonal antibody for WB, IHC, IP, FC
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4-8 cell stage mouse embryos.
Stage specific embryonic antigen4antibody; Rat Anti-SSEA-3 Monoclonal Antibody; Anti-SSEA-3 Monoclonal Antibody; SSEA-3 Monoclonal Antibody Rat Anti-SSEA-3 MAb; Anti-SSEA-3 MAb; SSEA-3 MAb
SSEA3 is a globoseries carbohydrate antigen present on both cell surface glycolipids and glycopeptides. It is found on the surface of mouse oocytes, becoming restricted to the intracellular mass of the early blastocyst and then to the primitive endoderm. It is present on the surface of human teratocarcinoma cells (EC), embryonic germ cells (EG) and embryonic stem cells (ES) but not mouse undifferentiated mouse cells of these types. SSEA3 expression decreases as human EC, ES and EG cells differentiate but increases on differentiation of mouse EC, ES and EG cells. It is also found on the surface of mouse erythrocytes.
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Kim, HO; Huh, YJ; et al. Selective Depletion of SSEA-3-and TRA-1-60-Positive Undifferentiated Human Embryonic Stem Cells by Magnetic Activated Cell Sorter (MACS). TISSUE ENGINEERING AND REGENERATIVE MEDICINE 8:253-261(2011).
Miki, T; Mitamura, K; et al. Identification of stem cell marker-positive cells by immunofluorescence in term human amnion. JOURNAL OF REPRODUCTIVE IMMUNOLOGY 75:91-96(2007).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.