Specifications
Species Reactivity
Human; Mouse
Immunogen
A synthesized peptide derived from human SRRM2
Applications
Application Notes
WB: 1:1000-3000
General Notes
This product (Catalog No. DPABH-21018) is a rabbit-derived polyclonal antibody raised against human SRRM2. This antibody exhibits cross-reactivity with SRRM2 from mouse. It has been affinity purified by Protein A. Enables C2H2 zinc finger domain binding activity. Involved in mRNA splicing, via spliceosome. Located in Cajal body and nuclear speck. Part of U2-type catalytic step 2 spliceosome and U2-type precatalytic spliceosome. Implicated in autosomal dominant intellectual developmental disorder 72. Biomarker of Parkinson's disease.
DPABH-21018 is suitable for use in Western blot (WB) (1:1,000–1:3,000) application.
DPABH-21018 is supplied as a liquid formulation in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
SRRM2, 300 kDa nuclear matrix antigen, 300-KD, Cwc21, KIAA0324, RNA binding protein, SRm300, TaxREB803, SRL300, CWF21
Citations
Publication ()
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