Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Full length native protein (purified) corresponding to Human beta 1 Spectrin. Purified human erythrocyte beta-1 spectrin.
Applications
Application Notes
Flow Cyt: 2μg/106 cells; IHC-P: 5 μg/ml; ICC: 1/10 - 1/200; ICC/IF: 1/25; WB: 1/100; IHC-P: 1/20 - 1/200.
Target
Alternative Names
SPTB; spectrin, beta, erythrocytic; spectrin beta chain, erythrocyte; spherocytosis; clinical type I; beta-I spectrin; membrane cytoskeletal protein; EL3; HS2; SPH2; HSPTB1;
Product Background
Antigen Description
Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.
Pathway
Axon guidance, organism-specific biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem;
Citations
Publication ()
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COA
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