Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Sprouty 4 aa 200 to the C-terminus. The exact sequence is proprietary.Database link: Q9C004
Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras.
My Review for Anti-SPRY4 monoclonal antibody, clone FQS23238
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