SPPL2A (NP_116191, 31 a.a. ~ 129 a.a) partial recombinant protein with GST tag. The sequence is HASGNGTTKDYCMLYNPYWTALPSTLENATSISLMNLTSTPLCNLSDIPPVGIKSKAVVV PWGSCHFLEKARIAQKGGAEAMLVVNNSVLFPPSGNRSE
Conjugate
Unconjugated
Target
Alternative Names
SPPL2A; signal peptide peptidase like 2A; IMP3; PSL2; signal peptide peptidase-like 2A; IMP-3; SPP-like 2A; intramembrane protease 3; presenilin-like protein 2; intramembrane cleaving protease;
This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.
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