A synthetic peptide of human SPO11 is used for rabbit immunization.
Conjugate
Unconjugated
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Alternative Names
SPO11; SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae); SPO11 meiotic protein covalently bound to DSB like (S. cerevisiae) , SPO11, meiotic protein covalently bound to DSB (S. cerevisiae) like; meiotic recombination protein SPO11; ca
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5 end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
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