General Notes
This product (Catalog No. DPABH-19881) is a rabbit-derived polyclonal antibody raised against human SPINK1, targeting the amino acid region 24–79 of the protein. It has been affinity purified by Protein A. SPINK1 is a protein-coding gene located on the long arm of chromosome 5 (5q32) that encodes serine peptidase inhibitor Kazal type 1, also known as pancreatic secretory trypsin inhibitor (PSTI) or tumor-associated trypsin inhibitor (TATI). This 56-amino-acid mature protein is secreted by pancreatic acinar cells into pancreatic juice, where it functions as a potent inhibitor of trypsin, preventing the premature activation of digestive enzyme zymogens and thereby protecting pancreatic tissue from autodigestion. The gene spans approximately 14.6 kb with six exons and is highly expressed in the pancreas and gastric mucosa.
DPABH-19881 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-19881 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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