Rabbit Anti-Human SPDYC (a.a. 1-293) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human SPDYC protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-293 aa of BC137244

Conjugate

Application Notes

IHC: 1:250-1:1000

General Notes

This product (Catalog No. DPABH-20902) is a rabbit-derived polyclonal antibody raised against human SPDYC, targeting the amino acid region 1–293 of the protein. It has been affinity purified by Protein A. SPDYC(Speedy protein C), also known as RINGOC and Ringo2, promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Downregulation of SPDYC inhibits cell growth, reduces the fraction of cells in G1, and increases the S and G2 populations(PMID: 18802405). SPDYC is involved in the spindle-assembly checkpoint and required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores(Uniprot).
DPABH-20902 is suitable for use in IHC (1:250–1:1,000) application.
DPABH-20902 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

hSpy/Ringo C; RINGO C; Ringo2; SPDYC; Speedy protein C

Entrez Gene ID

UniProt ID