Rabbit Anti-Human SPATA5L1 (a.a. 1-351) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human SPATA5L1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-351 aa of BC000981

Conjugate

Application Notes

WB: 1:500-1:1000

General Notes

This product (Catalog No. DPABH-22759) is a rabbit-derived polyclonal antibody raised against human SPATA5L1, targeting the amino acid region 1–351 of the protein. It has been affinity purified by Protein A. SPATA5L1 (Spermatogenesis-associated protein 5-like protein 1) belongs to the AAA+ATPase protein superfamily. A full-length SPATA5L1 transcript and a short SPATA5L1 variant can be produced in human by alternative splicing. Bi-allelic SPATA5L1 variants lead to a human disease characterized by sensorineural hearing loss with or without a nonprogressive mixed neurodevelopmental phenotype. And immunofluorescence analysis in rat hippocampal neurons demonstrated that SPATA5L1 was located in neuronal and glial cell nuclei, with more prominent expression in neurons (PubMed:34626583). SPATA5L1 also has 3 isoforms.
DPABH-22759 is suitable for use in Western blot (WB) (1:500–1:1,000) application.
DPABH-22759 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

SPATA5L1; Spermatogenesis-associated protein 5-like protein 1

Entrez Gene ID

UniProt ID