Anti-SOCS3 monoclonal antibody (DCABH-933)
Mouse anti-Human SOCS3 monoclonal antibody for WB, FC
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
7G4
Species Reactivity
Human
Immunogen
Recombinant full length Human SOCS3 produced in HEK293T cells (NP_003946).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500; Flow Cyt: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Target
Alternative Names
SOCS3; suppressor of cytokine signaling 3; CIS3; Cish3; SOCS 3; SSI 3
Entrez Gene ID
UniProt ID
Product Background
Pathway
ATF-2 transcription factor network, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem;
Citations
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References
Nakaya, M; Hamano, S; et al. Aberrant IL-4 production by SOCS3-over-expressing T cells during infection with Leishmania major exacerbates disease manifestations. INTERNATIONAL IMMUNOLOGY 23:195-202(2011).
Shouda, T; Yoshida, T; et al. Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis. JOURNAL OF CLINICAL INVESTIGATION 108:1781-1788(2001).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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