SRCIN1 (SRC kinase signaling inhibitor 1) is a protein-coding gene. Diseases associated with SRCIN1 include cystoisosporiasis, and paraphimosis. GO annotations related to this gene include protein kinase binding and protein domain specific binding. An important paralog of this gene is KIAA1217. Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
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