Anti-SNF8 (aa 23-122) polyclonal antibody

Species Reactivity

Human

Immunogen

SNF8 (NP_009172, 23 a.a. ~ 122 a.a) partial recombinant protein with GST tag. The sequence is ERGTVLAEDQLAQMSKQLDMFKTNLEEFASKHKQEIRKNPEFRVQFQDMCATIGVDPLAS GKGFWSEMLGVGDFYYELGVQIIEVCLALKHRNGGLITLE

Conjugate

Alternative Names

SNF8; SNF8, ESCRT-II complex subunit; Dot3; EAP30; VPS22; vacuolar-sorting protein SNF8; hVps22; EAP30 subunit of ELL complex; ESCRT-II complex subunit VPS22; ELL-associated protein of 30 kDa; SNF8, ESCRT-II complex subunit, homolog;

Entrez Gene ID

UniProt ID

Antigen Description

SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741]; Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM, Mar 2008]

Pathway

ESCRT-II complex; Endocytosis; Endosomal Sorting Complex Required For Transport (ESCRT);