Recombinant full length protein corresponding to Human SNAPIN aa 1-136. (AAH04494).Sequence: MAGAGSAAVSGAGTPVAGPTGRDLFAEGLLEFLRPAVQQLDSHVHAVRES QVELREQIDNLATELCRINEDQKVALDLDPYVKKLLNARRRVVLVNNILQ NAQERLRRLNHSVAKETARRRAMLDSGIYPPGSPGK Database link: O95295
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
SNAPIN; SNAP-associated protein; SNAPAP; SNARE-associated protein Snapin; SNAP 25 binding protein; snapin; SNAP-25-binding protein; SNARE associated protein snapin; synaptosomal-associated protein 25-binding protein;
May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release by potentiating the interaction of synaptotagmins with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells.
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