Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Recombinant fragment within Human SNAP47. The exact sequence is proprietary.Database link: Q5SQN1
Applications
Application Notes
WB: 1/1000 - 1/5000; IHC-P: 1/50 - 1/100; Flow Cyt: 1/100 - 1/500;
Target
Alternative Names
SNAP47; synaptosomal-associated protein, 47kDa; C1orf142, chromosome 1 open reading frame 142; synaptosomal-associated protein 47; SNAP 47; SVAP1; epididymis luminal protein 170; synaptosomal-associated 47 kDa protein; HEL170; SNAP-47; C1orf142; FLJ12517
Product Background
Antigen Description
SNAP47 belongs to the SVAP1 family. It contains two t-SNARE coiled-coil homology domains. SNAP47 has ubiquitous tissue distribution, with particularly high levels in nervous tissue. In neurons, SNAP 47 has been shown to have widespread distribution on intracellular membranes and is enriched in synaptic vesicle fractions. In vitro, SNAP 47 can substitute for SNAP-25 in SNARE complex formation, but not as efficiently.
Pathway
SNARE interactions in vesicular transport, organism-specific biosystem; SNARE interactions in vesicular transport, conserved biosystem;
Citations
Publication ()
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