Specifications
Species Reactivity
Mouse; Human; Xenopus laevis
Immunogen
Recombinant full length His 6 tagged SMN protein (Human).
Applications
Application Notes
IHC-P: 5 μg/ml; Flow Cyt: 1μg/106 cells.
Target
Alternative Names
SMN1; survival of motor neuron 1, telomeric; SMA, SMA@, spinal muscular atrophy (Werdnig Hoffmann disease, Kugelberg Welander disease); survival motor neuron protein; BCD541; SMA1; SMA2; SMA3; SMNT; gemin 1; gemin-1; component of gems 1; SMA; SMN; SMA4;
Product Background
Antigen Description
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.
Pathway
Gene Expression, organism-specific biosystem; Metabolism of non-coding RNA, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Survival motor neuron (SMN) complex, organism-specific biosystem; snRNP Assembly, organism-specific biosystem;
Citations
Publication ()
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COA
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