Anti-SMAD2 monoclonal antibody (DCABH-563)

Mouse anti-Human SMAD2 monoclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
3D21
Species Reactivity
Human
Immunogen
Recombinant full length Human Smad2 protein produced in HEK293T cells (NP_005892).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SMAD2; SMAD family member 2; MAD, mothers against decapentaplegic homolog 2 (Drosophila) , MADH2, SMAD, mothers against DPP homolog 2 (Drosophila); mothers against decapentaplegic homolog 2; JV18 1; MADR2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem;

Citations


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References


Fineschi, S; Cozzi, F; et al. Anti-fibroblast antibodies detected by cell-based ELISA in systemic sclerosis enhance the collagenolytic activity and matrix metalloproteinase-1 production in dermal fibroblasts. RHEUMATOLOGY 46:1779-1785(2007).
Tardif, G; Reboul, P; et al. Transforming growth factor-beta induced collagenase-3 production in human osteoarthritic chondrocytes is triggered by smad proteins: Cooperation between activator protein-1 and PEA-3 binding sites. JOURNAL OF RHEUMATOLOGY 28:1631-1639(2001).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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