Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Pathway
SLC-mediated transmembrane transport; Sodium/Proton exchangers; Transmembrane transport of small molecules; Transport of inorganic cations/anions and amino acids/oligopeptides;
Citations
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