Specifications
Immunogen
Full length Human SLC9A3R2 fused to maltose binding protein.
Applications
Application Notes
WB: 1/100.
Target
Alternative Names
SLC9A3R2; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2 , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator
Product Background
Antigen Description
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.
Pathway
Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; LPA receptor mediated events, organism-specific biosystem; PDGFR-beta signaling pathway, organism-specific biosystem;
Citations
Publication ()
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