SLC38A2 (solute carrier family 38, member 2) is a protein-coding gene. Diseases associated with SLC38A2 include adult syndrome, and temporal lobe epilepsy, and among its related super-pathways are Amino acid transport across the plasma membrane and Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell. GO annotations related to this gene include amino acid transmembrane transporter activity and symporter activity. An important paralog of this gene is SLC38A4. Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.
Pathway
Amino acid transport across the plasma membrane; Endochondral Ossification; GABAergic synapse; Glutamate Neurotransmitter Release Cycle; Glutamatergic synapse; Neuronal System; Neurotransmitter Release Cycle; Protein digestion and absorption; SLC-mediated transmembrane transport; Transmembrane transport of small molecules.
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