General Notes
This product (Catalog No. DPABH-18455) is a rabbit-derived IgG polyclonal antibody raised against human SLC33A1, targeting the amino acid region 481–549 of the protein. This antibody exhibits cross-reactivity with SLC33A1 from mouse and rat. It has been affinity purified by Protein A. The protein encoded by this gene is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene.
DPABH-18455 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500), ELISA (1:5,000–1:10,000) applications.
DPABH-18455 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
AT-1; Solute carrier family 33, member 1; SLC33A1; ACATN; Acetyl CoA transporter; Acetyl Coenzyme A transporter; AT 1; AT1; Human Angiotensin II Type 1 Receptor; Solute carrier family 33 (acetyl CoA transporter) member 1; Solute carrier family 33 member 1; spastic paraplegia 42 (autosomal dominant); SPG42; ACATN_HUMAN; Acetyl coenzyme A transporter 1; Acetyl-CoA transporter 1; Acetyl-coenzyme A transporter 1; Slc33a1; Solute carrier family 33 (acetyl CoA transporter) member 1