Specifications
Immunogen
SLC30A5 (AAH00808.1, 1 a.a. ~ 118 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
SLC30A5; solute carrier family 30 (zinc transporter), member 5; zinc transporter 5; FLJ12496; FLJ12756; MGC5499; ZnT 5; ZNT5; ZNTL1; ZTL1; zinc transporter ZTL1; znT-like transporter 1; ZnT-5;
Product Background
Antigen Description
Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP.
Pathway
Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Insulin Synthesis and Processing, organism-specific biosystem; Metal ion SLC transporters, organism-specific biosystem; SLC-mediated transmembrane transport, organism-sp
Citations
Publication ()
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COA
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